RMS-07
Product Specifications
CAS Number
2645409-78-3
Target
Kinesin, Others
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
RMS-07, a covalent inhibitor of Monopolar Spindle Kinase 1 (MPS1/TTK), exhibits a potent inhibitory concentration (IC50) of 13.1 nM. Specifically, it targets a poorly conserved cysteine located in the hinge region of the kinase.
Smiles
C(NC1=C(CC)C=CC=C1CC)(=O)C2=C3N(C=4C(CC3)=CN=C(NC5=C(NC(C=C)=O)C=C(C=C5)N6CCN(C)CC6)N4)C=C2
Molecular Formula
C35H40N8O2
Molecular Weight
604.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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