ABD957
Product Specifications
CAS Number
3007772-60-0
Target
Others, MAGL
Related Pathways
Others, Metabolism
Bioactivity
ABD957, a potent and selective covalent inhibitor of the ABHD17 depalmitoylase family, exhibits an IC 50 value of 0.21 μM against ABHD17B. This compound effectively inhibits N-Ras signaling and suppresses the growth of NRAS-mutant AML cells.
Smiles
C[C@H]1CN(CCN1C(=O)N2C=CC(=N2)S(=O)(=O)N(C)C)CC3=C(C=C(C=C3)C(F)(F)F)N4C5CCC4CN(C5)CC(=O)O
Molecular Formula
C27H36F3N7O5S
Molecular Weight
627.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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