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ABD957

Product Specifications

CAS Number

3007772-60-0

Target

Others, MAGL

Related Pathways

Others, Metabolism

Bioactivity

ABD957, a potent and selective covalent inhibitor of the ABHD17 depalmitoylase family, exhibits an IC 50 value of 0.21 μM against ABHD17B. This compound effectively inhibits N-Ras signaling and suppresses the growth of NRAS-mutant AML cells.

Smiles

C[C@H]1CN(CCN1C(=O)N2C=CC(=N2)S(=O)(=O)N(C)C)CC3=C(C=C(C=C3)C(F)(F)F)N4C5CCC4CN(C5)CC(=O)O

Molecular Formula

C27H36F3N7O5S

Molecular Weight

627.68

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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