Erasin
Product Specifications
Target
STAT, Apoptosis
Related Pathways
Stem Cells, JAK/STAT signaling, Apoptosis
Bioactivity
Erasin is a STAT3 inhibitor (IC50 = 9.7 μM) with higher selectivity for inhibiting STAT3 tyrosine phosphorylation than STAT5 and STAT1. It induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and is effective against Erlotinib-resistant cancer cells.
Smiles
CC(C)(C)C1=CC(C2=O)=C(C=C1)OC=C2/C=N/NC(C3=CC=CN=C3)=O
Molecular Formula
C20H19N3O3
Molecular Weight
349.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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