PF-184
Product Specifications
Target
IκB/IKK, Others
Related Pathways
NF-κB, Others
Bioactivity
PF-184 is a potent, selective inhibitor of IKK-2 with an IC50 value of 37 nM, demonstrating significant selectivity over rhIKK-1, IKKi, and over 30 other tyrosine and serine/threonine kinases. It is utilized in inflammation research, including studies on asthma and chronic obstructive pulmonary disease.
Smiles
C[C@@]1([C@](C)(CN(C2=NC=C(Cl)C(C(NC(C=C3)=CC4=C3CCC(C(C(N)=O)=N5)=C4N5C6=CC=C(F)C=C6)=O)=C2)C1)CO)CO
Molecular Formula
C32H32ClFN6O4
Molecular Weight
619.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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