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PF-184

Product Specifications

Target

I?B/IKK|||Others

Related Pathways

NF-?B|||Others

Bioactivity

PF-184 is a potent, selective inhibitor of IKK-2 with an IC50 value of 37 nM, demonstrating significant selectivity over rhIKK-1, IKKi, and over 30 other tyrosine and serine/threonine kinases. It is utilized in inflammation research, including studies on asthma and chronic obstructive pulmonary disease.

Smiles

C[C@@]1([C@](C)(CN(C2=NC=C(Cl)C(C(NC(C=C3)=CC4=C3CCC(C(C(N)=O)=N5)=C4N5C6=CC=C(F)C=C6)=O)=C2)C1)CO)CO

Molecular Formula

C32H32ClFN6O4

Molecular Weight

619.09

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/62151386460061739/T73470

Available Sizes

Curated Selection

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