LWG-301
Product Specifications
Target
Others|||Apoptosis|||Glutaminase
Related Pathways
Proteases/Proteasome|||Others|||Apoptosis
Bioactivity
LWG-301, an allosteric inhibitor of Glutaminase 1 (GLS1), demonstrates a potent inhibition with an IC50 value of 7 nM. It effectively impedes glutamine metabolism and elevates intracellular ROS levels, thereby inducing apoptosis. Additionally, LWG-301 shows moderate antitumor efficacy in the HCT116 xenograft model.
Smiles
CCCCC(=O)NC1=NN=C(S1)NC2CCN(CC2)C3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OCCCC
Molecular Formula
C28H38N8O3S
Molecular Weight
566.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/62151386460061727/T73458
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1339349-01 0.02 mg (E-Coli)
Recombinant Pseudomonas fluorescens Thymidylate kinase (tmk)
Ask
View Details MBS1339349-02 0.1 mg (E-Coli)
Recombinant Pseudomonas fluorescens Thymidylate kinase (tmk)
Ask
View Details MBS1339349-03 0.02 mg (Yeast)
Recombinant Pseudomonas fluorescens Thymidylate kinase (tmk)
Ask
View Details MBS1339349-04 0.1 mg (Yeast)
Recombinant Pseudomonas fluorescens Thymidylate kinase (tmk)
Ask
View Details