Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

LWG-301

Product Specifications

Target

Others|||Apoptosis|||Glutaminase

Related Pathways

Proteases/Proteasome|||Others|||Apoptosis

Bioactivity

LWG-301, an allosteric inhibitor of Glutaminase 1 (GLS1), demonstrates a potent inhibition with an IC50 value of 7 nM. It effectively impedes glutamine metabolism and elevates intracellular ROS levels, thereby inducing apoptosis. Additionally, LWG-301 shows moderate antitumor efficacy in the HCT116 xenograft model.

Smiles

CCCCC(=O)NC1=NN=C(S1)NC2CCN(CC2)C3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OCCCC

Molecular Formula

C28H38N8O3S

Molecular Weight

566.72

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/62151386460061727/T73458

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Recombinant Human Fibroblast Growth Factor Receptor Substrate 2 (FRS2)

RPU41458-01 50 µg

Recombinant Human Fibroblast Growth Factor Receptor Substrate 2 (FRS2)

Ask

Recombinant Human Fibroblast Growth Factor Receptor Substrate 2 (FRS2)

RPU41458-02 100 µg

Recombinant Human Fibroblast Growth Factor Receptor Substrate 2 (FRS2)

Ask

Recombinant Human Fibroblast Growth Factor Receptor Substrate 2 (FRS2)

RPU41458-03 1 mg

Recombinant Human Fibroblast Growth Factor Receptor Substrate 2 (FRS2)

Ask

Mouse Monoclonal AMPK beta 2/PRKAB2 Antibody (OTI4H4) [FITC]

NBP2-71226F 0.1 mL

Mouse Monoclonal AMPK beta 2/PRKAB2 Antibody (OTI4H4) [FITC]

Ask

MFSD10-set siRNA/shRNA/RNAi Lentivector (Human)

28450091 4 x 500 ng

MFSD10-set siRNA/shRNA/RNAi Lentivector (Human)

Ask

mmu-miR-7656-3p miRNA Antagomir

MBS8320297-01 10 nmol

mmu-miR-7656-3p miRNA Antagomir

Ask