DRP1i27
Product Specifications
CAS Number
1453028-33-5
Target
Others, Dynamin
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
DRP1i27, a potent human dynamin-related protein 1 (Drp1) inhibitor, targets the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. It mitigates Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.
Smiles
C(N1[C@]2(CN(CC3=C(C)N=CN3)C[C@@](C1)(CC2)[H])[H])C=4OC(=CC4)C=5C=CNN5
Molecular Formula
C20H26N6O
Molecular Weight
366.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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