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DRP1i27

Product Specifications

CAS Number

1453028-33-5

Target

Others, Dynamin

Related Pathways

Cytoskeletal Signaling, Others

Bioactivity

DRP1i27, a potent human dynamin-related protein 1 (Drp1) inhibitor, targets the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. It mitigates Drp1-mediated mitochondrial fission in cell line models and offers protection against simulated ischemia-reperfusion injury.

Smiles

C(N1[C@]2(CN(CC3=C(C)N=CN3)C[C@@](C1)(CC2)[H])[H])C=4OC(=CC4)C=5C=CNN5

Molecular Formula

C20H26N6O

Molecular Weight

366.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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