What is the catalog number for CZS-241?

The catalog number for CZS-241 is T73449.

What sizes are available for CZS-241?

CZS-241 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does CZS-241 come in?

CZS-241 is available in 3 different pack sizes.

CZS-241 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CZS-241?

CZS-241 is manufactured by Molfinity.

What is the estimated delivery time for CZS-241?

Estimated delivery time for CZS-241 is approximately 10 business day(s), depending on your location.

CZS-241

Product Specifications

Target

PLK, Apoptosis, Others, Trk receptor

Related Pathways

Others, Tyrosine Kinase/Adaptors, Apoptosis, Cell Cycle/Checkpoint

Bioactivity

CZS-241 is an orally active, selective Polo-like Kinase (PLK) 4 inhibitor with an IC 50 of 2.6 nM that also inhibits TRKA at an IC 50 of 2.74 μM. It induces apoptosis and causes cell cycle arrest at the S/G2 phase, demonstrating potent antiproliferative effectiveness against leukemia cell lines while maintaining safety towards normal cell lines.