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NP10679

Product Specifications

CAS Number

2914889-88-4

Target

Cytochromes P450, Potassium Channel, Histamine Receptor, NMDAR

Related Pathways

Metabolism, Neuroscience, GPCR/G Protein, Immunology/Inflammation, Membrane transporter/Ion channel

Purity

0.9943

Bioactivity

NP10679 is an orally available, selective, brain-penetrating, potent, and pH-sensitive N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit.NP10679 inhibits histamine H1, hERG channels, and CYP enzymes, and may be useful in the study of epilepsy and ischemic stroke.

Smiles

O(C[C@@H](CN1CCN(CC1)C2=CC=C(C(F)(F)F)C=C2)O)C=3C=C4C(=CC3)NC(=O)CC4

Molecular Formula

C23H26F3N3O3

Molecular Weight

449.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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