NP10679
Product Specifications
CAS Number
2914889-88-4
Target
Cytochromes P450, Potassium Channel, Histamine Receptor, NMDAR
Related Pathways
Metabolism, Neuroscience, GPCR/G Protein, Immunology/Inflammation, Membrane transporter/Ion channel
Purity
0.9943
Bioactivity
NP10679 is an orally available, selective, brain-penetrating, potent, and pH-sensitive N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit.NP10679 inhibits histamine H1, hERG channels, and CYP enzymes, and may be useful in the study of epilepsy and ischemic stroke.
Smiles
O(C[C@@H](CN1CCN(CC1)C2=CC=C(C(F)(F)F)C=C2)O)C=3C=C4C(=CC3)NC(=O)CC4
Molecular Formula
C23H26F3N3O3
Molecular Weight
449.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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