TIM-063
Product Specifications
CAS Number
2493978-38-2
Target
CaMK, Others
Related Pathways
Others, Neuroscience
Bioactivity
TIM-063 is a selective, cell-permeable inhibitor of CaMKK that competes with ATP, directly targeting the catalytic domain of CaMKK. It exhibits K (i) values of 0.35 μM for CaMKKα and 0.2 μM for CaMKKβ, with respective IC (50) values of 0.63 μM and 0.96 μM.
Smiles
N(=O)(=O)C1=C2C3=C(C=4N(C(=O)C3=CC=C2)C=5C(N4)=CC=CC5)C=C1O
Molecular Formula
C18H9N3O4
Molecular Weight
331.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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