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VT02956

Product Specifications

CAS Number

2999763-09-4

Target

Others

Related Pathways

Others

Bioactivity

VT02956 is a LATS inhibitor (IC 50 : 0.76 nM for LATS1, 0.52 nM for LATS2) . VT02956 targets the Hippo pathway. VT02956 inhibits ESR1 expression and growth of ER+ breast cancer cell lines and patient-derived tumor organoids .

Smiles

C1CN(CCC1CN)C2=NC(=NC3=C(C=CC=C32)C#CCO)C4=CC=NC=C4

Molecular Formula

C22H23N5O

Molecular Weight

373.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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