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SP-471P

Product Specifications

CAS Number

2768011-36-3

Target

Others, DNA/RNA Synthesis, Anti-infection, Virus Protease

Related Pathways

Microbiology/Virology, Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair

Bioactivity

SP-471P is a potent inhibitor of dengue virus (DENV) protease, exhibiting half-maximal effective concentrations (EC50) of 5.9 μM for DENV1, 1.4 μM for DENV2, 5.1 μM for DENV3, and 1.7 μM for DENV4, with a cytotoxic concentration (CC50) greater than 100 μM. Additionally, SP-471P effectively reduces DENV viral RNA synthesis [1].

Smiles

BrC1=CC=CC(CN2C3=C(C=C(C4=CC(/C(N)=N/O)=CC=C4)C=C3)C5=C2C=CC(C6=CC(/C(N)=N/O)=CC=C6)=C5)=C1

Molecular Formula

C33H26BrN5O2

Molecular Weight

604.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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