SP-471P
Product Specifications
CAS Number
2768011-36-3
Target
Others|||DNA/RNA Synthesis|||Anti-infection|||Virus Protease
Related Pathways
Microbiology/Virology|||Cell Cycle/Checkpoint|||Others|||DNA Damage/DNA Repair
Bioactivity
SP-471P is a potent inhibitor of dengue virus (DENV) protease, exhibiting half-maximal effective concentrations (EC50) of 5.9 ?M for DENV1, 1.4 ?M for DENV2, 5.1 ?M for DENV3, and 1.7 ?M for DENV4, with a cytotoxic concentration (CC50) greater than 100 ?M. Additionally, SP-471P effectively reduces DENV viral RNA synthesis [1].
Smiles
BrC1=CC=CC(CN2C3=C(C=C(C4=CC(/C(N)=N/O)=CC=C4)C=C3)C5=C2C=CC(C6=CC(/C(N)=N/O)=CC=C6)=C5)=C1
Molecular Formula
C33H26BrN5O2
Molecular Weight
604.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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