MK-4541
Product Specifications
CAS Number
796885-38-6
Target
Others, Reductase, Androgen Receptor
Related Pathways
Endocrinology/Hormones, Others, Metabolism
Bioactivity
MK-4541 is an orally active, selective androgen receptor (AR) modulator that serves as an antagonist to inhibit 5α-reductase. It effectively inhibits proliferation and induces apoptosis in AR-positive prostate cancer cells, significantly reducing the growth of R3327-G prostate tumors in a xenograft mouse model.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@H](NC(OCC(F)(F)F)=O)CC4)[H])(CC[C@]1(N(C)C(=O)C=C2)[H])[H])[H]
Molecular Formula
C22H31F3N2O3
Molecular Weight
428.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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