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I-BET432

Product Specifications

Target

Others|||Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic|||Others

Bioactivity

I-BET432, a BET inhibitor, targets both the N-terminal (BD1) and C-terminal (BD2) bromodomains of BRD4, exhibiting pIC50 values of 7.5 and 7.2, respectively. As an orally administered candidate, I-BET432 holds potential for research in various oncology and inflammatory diseases.

Smiles

C[C@@H]1C2=C(C=C(C=C2)[C@H](CO)O)C(=CN(C1=O)C)C3=CN(N=C3)C

Molecular Formula

C18H21N3O3

Molecular Weight

327.38

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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