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TP-030-1

Product Specifications

CAS Number

2095514-75-1

Target

RIP kinase, Others

Related Pathways

Apoptosis, NF-κB, Others

Bioactivity

TP-030-1, an inhibitor of RIPK1, exhibits potent activity against hRIPK1 (human RIPK1) with a Ki value of 3.9 nM and against mRIPK1 (mouse RIPK1) with an IC50 value of 4.2 μM. This compound is instrumental in the research of inflammatory and neurodegenerative diseases.

Smiles

O=C1C=2C(=CN(CC3=CC=CC=C3)N2)CCN1[C@@H]4C(=O)N(C)C=5C(OC4)=CC=CC5

Molecular Formula

C23H22N4O3

Molecular Weight

402.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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