TP-030-1
Product Specifications
CAS Number
2095514-75-1
Target
RIP kinase|||Others
Related Pathways
Apoptosis|||NF-?B|||Others
Bioactivity
TP-030-1, an inhibitor of RIPK1, exhibits potent activity against hRIPK1 (human RIPK1) with a Ki value of 3.9 nM and against mRIPK1 (mouse RIPK1) with an IC50 value of 4.2 ?M. This compound is instrumental in the research of inflammatory and neurodegenerative diseases.
Smiles
O=C1C=2C(=CN(CC3=CC=CC=C3)N2)CCN1[C@@H]4C(=O)N(C)C=5C(OC4)=CC=CC5
Molecular Formula
C23H22N4O3
Molecular Weight
402.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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