GNE-2256
Product Specifications
CAS Number
2102170-43-2
Target
Others, IRAK
Related Pathways
NF-κB, Others, Immunology/Inflammation
Purity
0.9995
Bioactivity
GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
Smiles
N(C(=O)C1=C2N(N=C1)C=CC=N2)C3=C(C=C4C(=C3)CN(C[C@H](C(C)(C)O)F)C4=O)N5CCOCC5
Molecular Formula
C24H27FN6O4
Molecular Weight
482.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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