Articaine
Product Specifications
CAS Number
23964-58-1
Target
Sodium Channel, Others, NOD-like Receptor (NLR), NF-κB
Related Pathways
Immunology/Inflammation, Others, NF-κB, Membrane transporter/Ion channel
Bioactivity
Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-gated sodium channels located in the nerve's inner cavity. Furthermore, Articaine mitigates LPS-induced acute kidney injury through the suppression of NF-κB activation and inhibition of the NLRP3 inflammasome pathway.
Smiles
CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC
Molecular Formula
C13H20N2O3S
Molecular Weight
284.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15159795 1 Vial
Lentiviral mouse Msx2 shRNA (UAS) - Lentiviral mouse Msx2 shRNA (UAS, iRFP) (100)
Sign In for Pricing
View Details 
K6959803 1.0 µg DNA
Dapk3 sgRNA CRISPR Lentivector (Rat) (Target 2)
Sign In for Pricing
View Details 