Larotinib
Product Specifications
CAS Number
1438072-11-7
Target
BTK, EGFR, IRAK, Tyrosine Kinases
Related Pathways
Tyrosine Kinase/Adaptors, NF-κB, Angiogenesis, Immunology/Inflammation, JAK/STAT signaling
Purity
0.9973
Bioactivity
Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.
Smiles
N(C=1C2=C(C=C(OC)C(OCCCN3C[C@@]4([C@](C3)(OCCO4)[H])[H])=C2)N=CN1)C5=CC(Cl)=C(F)C=C5
Molecular Formula
C24H26ClFN4O4
Molecular Weight
488.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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