Larotinib

Product Specifications

CAS Number

1438072-11-7

Target

BTK|||EGFR|||IRAK|||Tyrosine Kinases

Related Pathways

Tyrosine Kinase/Adaptors|||NF-?B|||Angiogenesis|||Immunology/Inflammation|||JAK/STAT signaling

Purity

0.9973

Bioactivity

Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.

Smiles

N(C=1C2=C(C=C(OC)C(OCCCN3C[C@@]4([C@](C3)(OCCO4)[H])[H])=C2)N=CN1)C5=CC(Cl)=C(F)C=C5

Molecular Formula

C24H26ClFN4O4

Molecular Weight

488.94

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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