JAK-IN-24
Product Specifications
CAS Number
2042629-43-4
Target
JAK, Others
Related Pathways
Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, Others, Angiogenesis, JAK/STAT signaling
Bioactivity
JAK-IN-24, a JAK inhibitor, exhibits IC50 values of 0.534 nM and 24 nM in the presence of 4 μM and 1 mM ATP, respectively. Additionally, it effectively inhibits STAT5 phosphorylation induced by PBMC IL-15 with an IC50 of 86.171 nM.
Smiles
N(C1=C2C(NC=C2CCOCC#C)=NC=N1)[C@H]3CN(C(C=C)=O)[C@@H](C)CC3
Molecular Formula
C20H25N5O2
Molecular Weight
367.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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