DHFR-IN-5
Product Specifications
CAS Number
1142407-81-5
Target
DHFR|||Others
Related Pathways
DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others|||Metabolism
Bioactivity
DHFR-IN-5, an orally active and potent inhibitor of dihydrofolate reductase (DHFR), exhibits a K_i value of 0.54 nM against the quadruple mutant Plasmodium falciparum DHFR, demonstrating anti-malarial activity.
Smiles
O(CCCOC1=C(CCC(O)=O)C=CC=C1)C=2C(CC)=NC(N)=NC2N
Molecular Formula
C18H24N4O4
Molecular Weight
360.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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