PARL-IN-1
Product Specifications
Target
PTEN|||Mitophagy|||Others
Related Pathways
PI3K/Akt/mTOR signaling|||Others|||Autophagy
Bioactivity
PARL-IN-1, a potent PARL inhibitor, exhibits an IC50 value of 28 nM. It effectively inhibits PARL, consequently robustly activating the PINK1/Parkin pathway and promoting PINK1/Parkin-dependent mitophagy.
Smiles
C[C@@H](C(=O)C(=O)CNCCCCC1=CC=CC=C1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)C
Molecular Formula
C40H58N6O7
Molecular Weight
734.92
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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