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TrkA-IN-3

Product Specifications

Target

Others, Trk receptor

Related Pathways

Tyrosine Kinase/Adaptors, Others

Bioactivity

TrkA-IN-3 is a potent, subselective, and allosteric inhibitor of TrkA with an IC50 of 22.4 nM, demonstrating over 8000-fold selectivity towards TrkA compared to TrkB and TrkC, making it valuable for pain research.

Smiles

CN1C=CC(=N1)C2=C(C=CC(=C2)C(=O)NC3=C(N=CC(=C3)C(=O)O)C4=CC=CC=C4)C(F)(F)F

Molecular Formula

C24H17F3N4O3

Molecular Weight

466.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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