TrkA-IN-3
Product Specifications
Target
Others, Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors, Others
Bioactivity
TrkA-IN-3 is a potent, subselective, and allosteric inhibitor of TrkA with an IC50 of 22.4 nM, demonstrating over 8000-fold selectivity towards TrkA compared to TrkB and TrkC, making it valuable for pain research.
Smiles
CN1C=CC(=N1)C2=C(C=CC(=C2)C(=O)NC3=C(N=CC(=C3)C(=O)O)C4=CC=CC=C4)C(F)(F)F
Molecular Formula
C24H17F3N4O3
Molecular Weight
466.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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