BTK-IN-17
Product Specifications
Target
Others|||BTK
Related Pathways
Angiogenesis|||Others|||Tyrosine Kinase/Adaptors
Bioactivity
BTK-IN-17 is a selective, orally active inhibitor of Bruton's Tyrosine Kinase (BTK) with an inhibition concentration (IC50) value of 13.7 nM. It effectively reduces the expression of phosphorylated BTK at Tyrosine 223 (p-BTK Y223) and phosphorylated Phospholipase C Gamma 2 at Tyrosine 1217 (p-PLC?2 Y1217), demonstrating anti-inflammatory properties.
Smiles
C=CC(=O)N1CC[C@H](C1)N2C3=C4C(=CN=C4NC=N3)C(=N2)NC5=CC=C(C=C5)OC6=CC=CC=C6
Molecular Formula
C26H23N7O2
Molecular Weight
465.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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