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TDI-11861

Product Specifications

CAS Number

2857049-72-8

Target

AChR, Others

Related Pathways

Others, Neuroscience

Bioactivity

TDI-11861, a second-generation soluble Adenylyl Cyclase (sAC, ADCY10) inhibitor, demonstrates slow dissociation rates and effectively inhibits sAC activity in cells, evidenced by an IC50 value of 5.5 nM.

Smiles

C(C=1C(=NN(C(F)F)C1)C=2C=C(Cl)N=C(N)N2)C3=C(OCCN4[C@H](CO)COCC4)C=CC=C3

Molecular Formula

C22H25ClF2N6O3

Molecular Weight

494.92

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Compound T128498
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Compound T128498
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GPR109B, NT (HCAR3, GPR109B, HCA3, HM74B, NIACR2, Hydroxycarboxylic acid receptor 3, Nicotinic acid receptor 2, G-protein coupled receptor 109B, G-protein coupled receptor HM74, G-protein coupled receptor HM74B, Niacin receptor 2) (MaxLight 650)
MBS6303664-01 0.1 mL

GPR109B, NT (HCAR3, GPR109B, HCA3, HM74B, NIACR2, Hydroxycarboxylic acid receptor 3, Nicotinic acid receptor 2, G-protein coupled receptor 109B, G-protein coupled receptor HM74, G-protein coupled receptor HM74B, Niacin receptor 2) (MaxLight 650)

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