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MHTT-IN-1

Product Specifications

CAS Number

2839311-21-4

Target

Huntingtin, Others

Related Pathways

Others, Neuroscience

Bioactivity

MHTT-IN-1 (Example 1) is a potent inhibitor of the mutant huntingtin protein (mHTT), which is primarily responsible for Huntington's disease (HD), an inherited autosomal dominant neurodegenerative disorder. This compound effectively reduces mHTT levels with an EC50 of 46 nM.

Smiles

O=C1C=C(N=C2SC(=CN12)N3CCNCC3)C4=NN5C=C(N=C5C(=C4)C)C

Molecular Formula

C18H19N7OS

Molecular Weight

381.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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