MHTT-IN-1
Product Specifications
CAS Number
2839311-21-4
Target
Huntingtin|||Others
Related Pathways
Others|||Neuroscience
Bioactivity
MHTT-IN-1 (Example 1) is a potent inhibitor of the mutant huntingtin protein (mHTT), which is primarily responsible for Huntington's disease (HD), an inherited autosomal dominant neurodegenerative disorder. This compound effectively reduces mHTT levels with an EC50 of 46 nM.
Smiles
O=C1C=C(N=C2SC(=CN12)N3CCNCC3)C4=NN5C=C(N=C5C(=C4)C)C
Molecular Formula
C18H19N7OS
Molecular Weight
381.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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