RET-IN-16
Product Specifications
CAS Number
2259657-48-0
Target
Others, c-RET
Related Pathways
Apoptosis, Others, Tyrosine Kinase/Adaptors
Bioactivity
RET-IN-16 is a potent, selective inhibitor of RET, exhibiting IC50 values of 3.98 nM for RET (WT), 8.42 nM for RET (M918T), 15.05 nM for RET (V804L), 7.86 nM for RET (V804M), 5.43 nM for RET-CCDC6, and 8.86 nM for RET-KIF5B, indicating its high efficacy across different RET mutations. It possesses anticancer properties.
Smiles
O(C1=C2C(=NC(=N1)C=3C=CC=NC3)NN=C2)C4=CC(C(NC5=CC(C(F)(F)F)=C(CN6CCN(C)CC6)C=C5)=O)=CC=C4C
Molecular Formula
C31H29F3N8O2
Molecular Weight
602.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
043555-FITC 200 µL
UBTD1 (UBTD1, Ubiquitin domain-containing protein 1) (FITC) discontinued
Sign In for Pricing
View Details 302854-HRP 200 µL
ZCCHC3 (Zinc Finger CCHC Domain-Containing Protein 3, ZCCHC3, C20orf99) (HRP) discontinued
Sign In for Pricing
View Details 
MBS9337929-01 48 Well
Human Putative uncharacterized protein C1orf137, C1orf137 ELISA Kit
Sign In for Pricing
View Details MBS9337929-02 96 Well
Human Putative uncharacterized protein C1orf137, C1orf137 ELISA Kit
Sign In for Pricing
View Details MBS9337929-03 5x 96 Well
Human Putative uncharacterized protein C1orf137, C1orf137 ELISA Kit
Sign In for Pricing
View Details MBS9337929-04 10x 96 Well
Human Putative uncharacterized protein C1orf137, C1orf137 ELISA Kit
Sign In for Pricing
View Details