Akt1-IN-1
Product Specifications
Target
Akt, Others
Related Pathways
Others, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling
Bioactivity
Akt1-IN-1 is a potent and selective inhibitor of Akt1, demonstrating an IC50 of 18.79 nM in MIA PaCa-2 cells, indicating its high efficacy in inhibiting this specific kinase. Notably, it shows no significant teratogenicity, hepatotoxicity, or cardiotoxicity (No Observed Adverse Effect Level > 100 μM), making it a viable candidate for anticancer research.
Smiles
CC1=CC=C(C=C1)S(=O)(=O)N2C3=C(C=C2COCC4=C(N=C(N=C4C(C)C)N(C)S(=O)(=O)C)C5=CC=C(CC5)F)C=NC=C3
Molecular Formula
C31H34FN5O5S2
Molecular Weight
639.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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