RET-IN-13
Product Specifications
CAS Number
2684258-54-4
Target
C-RET, Others
Related Pathways
Apoptosis, Others, Tyrosine Kinase/Adaptors
Bioactivity
RET-IN-13, a quinoline-based compound, effectively inhibits the RET kinase, demonstrating IC50 values of 0.5 nM for RET (WT) and 0.9 nM for RET (V804M) . It holds promise for research into tumors and intestinal diseases associated with abnormal RET activation.
Smiles
O(C)C1=CC2=C(C=C1OC)N=CC(=C2)C3=CC=C(CC(NC4=CC(C(F)(F)F)=C(CN5CCN(CC)CC5)C=C4F)=O)C=N3
Molecular Formula
C32H33F4N5O3
Molecular Weight
611.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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