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EZH2-IN-7

Product Specifications

CAS Number

2659225-28-0

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Bioactivity

EZH2-IN-7, a potent inhibitor of EZH2, addresses overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) that cause an abnormal increase in H3K27me3, contributing to the proliferation of various tumors, including breast cancer, prostate cancer, and leukemia. It shows promise for cancer research applications.

Smiles

C(NC(C1=C(SC)C=C(C)NC1=O)([2H])[2H])(=O)C=2C=3C(N([C@H](C)C4(CCC(OC)CC4)[H])C2C)=CC=C(C3)C=5C=NN(C)C5

Molecular Formula

C31H37D2N5O3S

Molecular Weight

563.75

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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