EZH2-IN-7
Product Specifications
CAS Number
2659225-28-0
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
EZH2-IN-7, a potent inhibitor of EZH2, addresses overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations) that cause an abnormal increase in H3K27me3, contributing to the proliferation of various tumors, including breast cancer, prostate cancer, and leukemia. It shows promise for cancer research applications.
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C(NC(C1=C(SC)C=C(C)NC1=O)([2H])[2H])(=O)C=2C=3C(N([C@H](C)C4(CCC(OC)CC4)[H])C2C)=CC=C(C3)C=5C=NN(C)C5
Molecular Formula
C31H37D2N5O3S
Molecular Weight
563.75
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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