USP7-797
Product Specifications
CAS Number
2413944-70-2
Target
DUB
Related Pathways
Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Ubiquitination
Purity
0.9618
Bioactivity
USP7-797 is a selective non-covalent active site USP7 inhibitor, inhibiting USP7 and ubiquitin binding, with anti-tumor, oral and high efficiency (IC50=0.44 nmol), it is effective on both wild-type and mutant p53 tumor cells, and can significantly inhibit the growth of tumor cells and induce apoptosis.
Smiles
CC1(C)C2C1C(=O)N(CC=3SC=4C(C3)=NC=CC4C5=C(C[C@@H]6CNCCO6)C(C)=CC(Cl)=C5)C2=O
Molecular Formula
C27H28ClN3O3S
Molecular Weight
510.05
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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