OTS193320
Product Specifications
CAS Number
2093401-33-1
Target
Apoptosis|||Histone Methyltransferase|||Others
Related Pathways
Chromatin/Epigenetic|||Others|||Apoptosis
Bioactivity
OTS193320, an imidazopyridine compound, acts as an inhibitor of SUV39H2 methyltransferase activity. It effectively reduces global histone H3 lysine 9 tri-methylation levels in breast cancer cells, promoting apoptotic cell death. When combined with Doxorubicin (DOX), OTS193320 enhances the reduction of ?-H2AX levels and decreases cancer cell viability more significantly than when either agent is used alone.
Smiles
O(C)C1=C(C2=CN3C(=N2)C=C(N[C@@H]4CC[C@H](NCC5=CC=C(N(=O)=O)C=C5)CC4)C=C3)C=C(Cl)C(OC)=C1
Molecular Formula
C28H30ClN5O4
Molecular Weight
536.02
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal KIR2DL3/CD158b2 Antibody (190IIC311) [Janelia Fluor 549]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP1-04316JF549 0.1 mL
Mouse Monoclonal KIR2DL3/CD158b2 Antibody (190IIC311) [Janelia Fluor 549]
Ask
View Details 
137843-FITC 100 µL
CHST11 (Carbohydrate Sulfotransferase 11, Chondroitin 4-O-sulfotransferase 1, C4ST1, C4ST-1, Chondroitin 4-sulfotransferase, C4ST, HSA269537) (FITC)
Ask
View Details