PD 168568
Product Specifications
CAS Number
210688-56-5
Target
Dopamine Receptor, Others
Related Pathways
GPCR/G Protein, Neuroscience, Others
Bioactivity
PD 168568, an orally active and potent dopamine receptor D4 (DRD4) antagonist featuring an isoindolinone structure, demonstrates selective affinity for the D4 receptor over D2 and D3 receptors, with K i values of 8.8, 1842, and 2682 nM, respectively. This compound is utilized in glioblastoma (GBM) research.
Smiles
C(CN1CCN(CC1)C2=CC(C)=C(C)C=C2)C3C=4C(C(=O)N3)=CC=CC4
Molecular Formula
C22H27N3O
Molecular Weight
349.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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