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DOCK2-IN-1

Product Specifications

CAS Number

4590-86-7

Target

Others

Related Pathways

Others

Bioactivity

DOCK2-IN-1, an analogue of CPYPP, effectively inhibits DOCK2 (IC50 = 19.1 μM) by reversibly binding to its DHR-2 domain, thereby hindering its catalytic function. This compound obstructs the activation of Rac in lymphocytes, triggered either by chemokine or antigen receptors. Consequently, DOCK2-IN-1 markedly reduces chemotactic responses and T cell activation [1].

Smiles

O=C1N(NC(=O)C1=CC2=C(Cl)C=CC=C2)C3=CC=CC=C3

Molecular Formula

C16H11ClN2O2

Molecular Weight

298.72

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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