EGFR-IN-74
Product Specifications
Target
EGFR, Others
Related Pathways
Others, Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Bioactivity
EGFR-IN-74 is a potent inhibitor targeting EGFR, specifically effective against the L858R/T790M mutations, exhibiting an IC50 value of 138 nM. It effectively induces apoptosis in cancer cells.
Smiles
CCOC(=O)C1=C(C2=C(C=CC(=C2)Br)N=C1N3C=CN=C3)N4CCN(CC4)C5=CC=CC=C5NS(=O)(=O)C6=CC=C(C=C6)C(F)(F)F
Molecular Formula
C32H28BrF3N6O4S
Molecular Weight
729.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx455780-01 50 µg
Interleukin 5 Receptor Subunit Alpha (IL5RA) Antibody
Sign In for Pricing
View Details abx455780-02 100 µg
Interleukin 5 Receptor Subunit Alpha (IL5RA) Antibody
Sign In for Pricing
View Details OR1036697 10 mg
(R) -4-methyl-N- ((R) -1- (((S) -4-methyl-1- ((R) -2-methyloxiran-2-yl) -1-oxopentan-2-yl) amino) -1-oxo-3-phenylpropan-2-yl) -2- ((S) -2- (2-morpholinoacetamido) -4-phenylbutanamido) pentanamide
Sign In for Pricing
View Details 583481 20 µg
Acetylcholine Receptor Subunit Alpha, Recombinant, Tetronarce Californica, aa25-234, His-Tag
Sign In for Pricing
View Details