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EGFR-IN-74

Product Specifications

Target

EGFR, Others

Related Pathways

Others, Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

Bioactivity

EGFR-IN-74 is a potent inhibitor targeting EGFR, specifically effective against the L858R/T790M mutations, exhibiting an IC50 value of 138 nM. It effectively induces apoptosis in cancer cells.

Smiles

CCOC(=O)C1=C(C2=C(C=CC(=C2)Br)N=C1N3C=CN=C3)N4CCN(CC4)C5=CC=CC=C5NS(=O)(=O)C6=CC=C(C=C6)C(F)(F)F

Molecular Formula

C32H28BrF3N6O4S

Molecular Weight

729.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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