EGFR-IN-74
Product Specifications
Target
EGFR|||Others
Related Pathways
Others|||Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling
Bioactivity
EGFR-IN-74 is a potent inhibitor targeting EGFR, specifically effective against the L858R/T790M mutations, exhibiting an IC50 value of 138 nM. It effectively induces apoptosis in cancer cells.
Smiles
CCOC(=O)C1=C(C2=C(C=CC(=C2)Br)N=C1N3C=CN=C3)N4CCN(CC4)C5=CC=CC=C5NS(=O)(=O)C6=CC=C(C=C6)C(F)(F)F
Molecular Formula
C32H28BrF3N6O4S
Molecular Weight
729.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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