FUBP1-IN-2
Product Specifications
CAS Number
1242862-71-0
Target
C-Myc|||Others
Related Pathways
Others|||Cell Cycle/Checkpoint
Bioactivity
FUBP1-IN-2 is a potent inhibitor of far upstream binding protein 1 (FUBP1), effectively disrupting the FUBP1-FUSE interaction in the KH4 domain as demonstrated in a gel shift assay. This compound also exhibits binding affinity to FUBP1 in ChIP assays. Furthermore, FUBP1-IN-2 significantly downregulates c-Myc mRNA and protein levels, upregulates p21 mRNA and protein levels, and depletes intracellular polyamines.
Smiles
C(O)(=O)C=1C=C(C=CC1NC(=O)C2=CC=C(OC)C=C2)N3CCN(CC3)C4=C(C)C=CC(Cl)=C4
Molecular Formula
C26H26ClN3O4
Molecular Weight
479.96
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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