FLT3-IN-18
Product Specifications
CAS Number
752191-77-8
Target
FLT, Others
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Others
Bioactivity
FLT3-IN-18, a potent and selective FLT3 inhibitor, exhibits an IC50 value of 0.003 μM. It effectively induces apoptosis and G1 phase cell cycle arrest, while inhibiting FLT3 and STAT5 phosphorylation. This compound holds potential for acute myeloid leukemia (AML) research.
Smiles
N(C1=C2C(N(C=N2)C3CCCC3)=NC(N[C@H]4CC[C@H](N)CC4)=N1)C5=CC=C(C=C5)N6CCOCC6
Molecular Formula
C26H36N8O
Molecular Weight
476.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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