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FLT3-IN-18

Product Specifications

CAS Number

752191-77-8

Target

FLT, Others

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, Others

Bioactivity

FLT3-IN-18, a potent and selective FLT3 inhibitor, exhibits an IC50 value of 0.003 μM. It effectively induces apoptosis and G1 phase cell cycle arrest, while inhibiting FLT3 and STAT5 phosphorylation. This compound holds potential for acute myeloid leukemia (AML) research.

Smiles

N(C1=C2C(N(C=N2)C3CCCC3)=NC(N[C@H]4CC[C@H](N)CC4)=N1)C5=CC=C(C=C5)N6CCOCC6

Molecular Formula

C26H36N8O

Molecular Weight

476.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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