PI3K-IN-28
Product Specifications
CAS Number
2747100-02-1
Target
Others, PI3K
Related Pathways
Others, PI3K/Akt/mTOR signaling
Bioactivity
PI3K-IN-28 is a potent PI3K inhibitor demonstrating high efficacy and lower toxicity in MCF-10a models. It exhibits half-maximal inhibitory concentration (IC50, μM) values of 5.8, 2.3, and 7.9. With a selectivity index (SI) of 39, PI3K-IN-28 emerges as a promising lead compound for the optimization of anticancer agents.
Smiles
N(/N=C/C1=CC=C(OS(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(=O)=O)C=C1)=C/2\N(C(=CS2)C3=CC=CC=C3)C4=CC=CC=C4
Molecular Formula
C26H16F9N3O3S2
Molecular Weight
653.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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