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(S) -HH2853

Product Specifications

CAS Number

2202678-05-3

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9974

Bioactivity

(S) -HH2853 is a potent dual inhibitor of EZH1 and EZH2, inhibiting EZH2_Y641F with an IC50 of <100 nM. (S) -HH2853 has potential antitumor activity and can be used in the study of autoimmune diseases.

Smiles

[C@H](C)(C=1N2C(=C(C=C2)C3=CC=C(C)N=N3)C=C(C(NCC4=C(OC)C=C(C)NC4=O)=O)C1C)N5CCN(CC(F)(F)F)CC5

Molecular Formula

C31H36F3N7O3

Molecular Weight

611.66

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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